All Leaders
Longevity & Biomarker ReversalProject Blueprint Clinical Protocols (protocol.bryanjohnson.com)

Bryan Johnson

Founder of Project Blueprint & Kernel

Tech Entrepreneur, Longevity Pioneer, Quantified-Self Record Holder (DunedinPACE)

Bryan Johnson Morning 4h46

Bryan Johnson is an American entrepreneur and longevity explorer who spends over $2M annually testing interventions to slow down biological aging. Through Project Blueprint, his 100+ clinical biomarkers are systematically tracked and shared as open-source human longevity protocols.

Core Philosophy:

Don't die. Measurable autonomous health through biological data, zero algorithmic self-harm, and full biomarker calibration.

"Autonomous self: let your organs speak through data and remove the conscious mind from bad health decisions."
Interactive Daily Actions Checklist (19)
PROTOCOL PROFILE METRICS
Total Actions
19
Daily Investment
~668m
Friction Score
1.8/5
Evidence Level
Grade A
Targeted Biomarkers & Clinical Objectives:
DunedinPACE Aging Rate < 0.65Resting Heart Rate < 48 bpmVO2 Max in Top 1% of 18-Year-OldsZero Plaque Calcium Score (CAC)

Neurobiological & Physiological Mechanisms

Peer-reviewed physiological pathways governing this daily routine.

01

Epigenetic Methylation Clocks (DunedinPACE)

Precisely calibrates cellular pathways to sustain high cognitive stamina and longevity.

02

Continuous Glucose & Insulin Homeostasis

Precisely calibrates cellular pathways to sustain high cognitive stamina and longevity.

03

Systemic Vascular Endothelial Function

Precisely calibrates cellular pathways to sustain high cognitive stamina and longevity.

04

Full Organ Biological Age Calibration

Precisely calibrates cellular pathways to sustain high cognitive stamina and longevity.

Interactive Daily Actions Checklist

Click any action to inspect scientific evidence or check items off to test your routine.

☀️Phase 1: Morning Awakening & Anchoring(12)
Sleep
5m

Morning Biomarker Tracking

biomarkers

Effort: 2/5
Light
6m

10,000 Lux Light Box

cortisol regulation

Effort: 1/5
Mindset
6m

Red Light / Laser Therapy

mitochondrial health

Effort: 1/5
Breath
6m

Blueprint Morning Breathwork

HRV

Effort: 1/5
Nutrition
2m

Creatine 5-7.5g + Electrolytes

brain health

Effort: 1/5
Nutrition
15m

High Protein Nut & Berry Bowl

polyphenols

Effort: 2/5
Nutrition
1m

Omega-3 EPA/DHA + D3/K2

cardiovascular health

Effort: 1/5
Movement
45m

Johnson 60min Movement Matrix

strength

Effort: 4/5
Mindset
5m

Skin & Scalp Protocol

skin barrier

Effort: 2/5
Cold / Heat
20m

Sauna 93°C with Head Cooling

cellular detox

Effort: 4/5
Mindset
5m

Oral Hygiene: Waterpik + Floss

cardiovascular health

Effort: 2/5
Mindset
1m

Tongue Scraping

vitality

Effort: 1/5
Phase 2: High Performance & Deep Work(2)
Nutrition
20m

Veggie & Legume Bowl

dietary fiber

Effort: 2/5
Nutrition
5m

Raw Nuts & Dark Berries Snack

brain health

Effort: 1/5
🌙Phase 3: Autonomic Downregulation & Sleep Prep(2)
Sleep
510m

8.5h In-Bed Window 20:30

cellular repair

Effort: 4/5
Mindset
3m

Floss & Gum Stimulation

arterial elasticity

Effort: 1/5
🔄Anytime / Intermittent Interventions(3)
Nutrition
2m

Track 35g+ Fiber Daily

gut microbiome

Effort: 2/5
Nutrition
1m

Extra Virgin Olive Oil 15-30ml

cardiovascular health

Effort: 1/5
Nutrition
10m

Weekly Supplements Review

consistency

Effort: 2/5
Medical & Experimental Protocol Disclaimer

These protocols reflect documented routines of public figures and scientific literature. They do not constitute personalized medical advice. Always consult a certified physician before starting deliberate cold exposure, thermal stress, or drastic supplement regimens.

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Or use instantly in your browseriOS 18+ • Public Beta Available
09:41
5G
TODAY PROTOCOL
Dr. Huberman Daily
32 LOAD
☀️
Morning Sunlight (10k lux)
07:00 • 15 min • SCN Clock
Delay Caffeine 90-120m
08:45 • Adenosine Clearance
🏃
Zone 2 Aerobic Base
11:00 • 45 min • Mito Density
🧘
NSDR Nervous Reset
14:00 • 20 min • Dopamine Reset
SwiftData Local Cache100% Encrypted